TOP
Nav Bar
  1. General Info
  2. Effects Info
  3. Reference
Drug Interaction Details
01. General Information
Pair Name Sulforaphane, Lapatinib
Phytochemical Name Sulforaphane (PubChem CID: 5350 )
Anticancer drug Name Lapatinib (PubChem CID: 208908 )
Structure of
Phytochemical
2D-img
Download
2D MOL 3D MOL
Structure of
Anticancer Drug
2D-img
Download
2D MOL 3D MOL
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
Hide/Show
Enhancing Drug Efficacy
Hide/Show
Combination Pair ID: 546
Pair Name Sulforaphane, Lapatinib
Disease Info [ICD-11: 2B72] Gastric cancer Investigative
Biological Phenomena Induction-->Blockade of cell cycle in G0/G1 phase
Gene Regulation Down-regulation Phosphorylation AKT1 hsa207
Down-regulation Phosphorylation ERBB2 hsa2064
Down-regulation Phosphorylation MAPK1 hsa5594
In Vitro Model SGC-7901 Human papillomavirus-related cervical adenocarcinoma Homo sapiens (Human) CVCL_0520
Result Therapeutic Mechanism of Lapatinib Combined with Sulforaphane on Gastric Cancer
03. Reference
No. Title Href
1 Therapeutic Mechanism of Lapatinib Combined with Sulforaphane on Gastric Cancer. Evid Based Complement Alternat Med. 2021 Sep 18;2021:9933274. doi: 10.1155/2021/9933274. Click
It has been 48674 visits since 2024.08
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang
TOP