Pair Name | Sulforaphane, Lapatinib | ||
Phytochemical Name | Sulforaphane (PubChem CID: 5350 ) | ||
Anticancer drug Name | Lapatinib (PubChem CID: 208908 ) | ||
Structure of Phytochemical |
Download
2D
MOL
3D
MOL
|
||
Structure of Anticancer Drug |
Download
2D
MOL
3D
MOL
|
Pair Name | Sulforaphane, Lapatinib | |||
Disease Info | [ICD-11: 2B72] | Gastric cancer | Investigative | |
Biological Phenomena | Induction-->Blockade of cell cycle in G0/G1 phase | |||
Gene Regulation | Down-regulation | Phosphorylation | AKT1 | hsa207 |
Down-regulation | Phosphorylation | ERBB2 | hsa2064 | |
Down-regulation | Phosphorylation | MAPK1 | hsa5594 | |
In Vitro Model | SGC-7901 | Human papillomavirus-related cervical adenocarcinoma | Homo sapiens (Human) | CVCL_0520 |
Result | Therapeutic Mechanism of Lapatinib Combined with Sulforaphane on Gastric Cancer |
No. | Title | Href |
---|---|---|
1 | Therapeutic Mechanism of Lapatinib Combined with Sulforaphane on Gastric Cancer. Evid Based Complement Alternat Med. 2021 Sep 18;2021:9933274. doi: 10.1155/2021/9933274. | Click |